![]() The automation of monitoring processes increase the biomass of cultures of cells allows to obtain more reliable results that will not depend on the operator. The measurement process takes place online without any interruption/disturbances of fermentation. The results of studies of mammalian cell culture during the fermentation process show that the system significantly reduces manual labour and associated measurement errors. Samples can be aspirated directly from syringes, pipettes, test tubes, flasks, or sample cups with a volume requirement of only 300 µL.The application of the new integrated multi-function analyzer BioProfile FLEX automated sampling system Data is also stored and can be retrieved for review at a later time as well as transmitted to an external computer. Test results are available in 45 seconds and can be printed. This dramatically reduces costs by eliminating the time and labor required to manually perform QC. This unique system combines multiple levels of controls and dedicated software, allowing any level of QC to be run at any time-either on a pre-programmed schedule or on demand. Other systems can pose significant waste handling hazards to operators.īioProfile pHOx features a completely automated QC system contained within a single on-board QC cartridge. A self-contained waste receptacle within the cartridge eliminates direct handling of waste and direct contact with hazardous biological materials. This compact, easy-to-use analyzer measures pH, PCO 2, and PO 2 in the appropriate ranges for cell culture and fermentation processes, and provides calculated values for total CO 2, bicarbonate, CO 2 saturation, and air saturation (dissolved oxygen).īioProfile pHOx analyzers measure only 12” wide byġ5” deep by 15” tall (31 cm x 38 cm x 38 cm), including on-board reagents and controls, as well as a sealed waste container to store used reagents and samples.Ĭartridge-Based Reagent Management System (RMS)īioProfile pHOx features smart reagent cartridges that are easy to use with simple snap-in replacement. BioProfile pHOx is the first analyzer designed specifically to provide rapid, accurate measurement of acid base and respiratory parameters in cell culture and fermentation samples. ![]()
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